| Top 15 Major Causes of Death, 2019 |
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Age-adjusted death rate (1) |
| Rank |
Cause of death |
Number of
deaths |
Rate |
Percent chang
from 2018 |
| 1 |
Heart disease |
659,041 |
161.5 |
-1.3% |
| 2 |
Malignant neoplasms (tumors) |
599,601 |
146.2 |
-1.9 |
| 3 |
Accidents (unintentional injuries) |
173,040 |
49.3 |
2.7 |
| 4 |
Chronic lower respiratory diseases |
156,979 |
38.2 |
-3.8 |
| 5 |
Cerebrovascular diseases (stroke) |
150,005 |
37.0 |
-0.3 |
| 6 |
Alzheimer's disease |
121,499 |
29.8 |
-2.3 |
| 7 |
Diabetes |
87,647 |
21.6 |
0.9 |
| 8 |
Kidney disease |
51,565 |
12.7 |
-1.6 |
| 9 |
Influenza and pneumonia |
49,783 |
12.3 |
-17.4 |
| 10 |
Intentional self-harm (suicide) |
47,511 |
13.9 |
-2.1 |
| 11 |
Chronic liver disease and cirrhosis |
44,358 |
11.3 |
1.8 |
| 12 |
Septicemia |
38,431 |
9.5 |
-6.9 |
| 13 |
Hypertension (2) |
36,524 |
8.9 |
(3) |
| 14 |
Parkinson disease |
35,311 |
8.8 |
1.1 |
| 15 |
Pneumonitis due to solids and liquids |
19,184 |
4.7 |
-2.1 |
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All other causes |
584,359 |
NA |
NA |
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All deaths |
2,854,838 |
715.2 |
1.2% |
(1) Per 100,000 population; factors out differences based on age.
(2) Essential (primary) hypertension and hypertensive renal disease.
(3) Less than 0.1 percent.
NA=Not applicable.
Source: National Center for Health Statistics. |
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