| Top 10 Leading Causes of Death, 2022 |
|
| Rank (1) |
Cause of death |
Number of
deaths |
Rate (2) |
| 1 |
Heart disease |
702,880 |
167.2 |
| 2 |
Malignant neoplasms (cancer) |
608,371 |
142.3 |
| 3 |
Accidents (unintentional injuries) |
227,039 |
64.0 |
| 4 |
COVID-19 |
186,552 |
44.5 |
| 5 |
Cerebrovascular diseases (stroke) |
165,393 |
39.5 |
| 6 |
Chronic lower respiratory diseases |
147,382 |
34.3 |
| 7 |
Alzheimer's disease |
120,122 |
28.9 |
| 8 |
Diabetes |
101,209 |
24.1 |
| 9 |
Kidney disease |
57,937 |
13.8 |
| 10 |
Chronic liver disease and cirrhosis |
54,803 |
13.8 |
| |
All other causes |
908,169 |
NA |
| |
All deaths |
3,279,857 |
798.8 |
(1) Based on number of deaths.
(2) Deaths per 100,000 U.S. standard population.
NA=Not applicable.
Source: National Center for Health Statistics, National Vital Statistics System, Mortality. |
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